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The Ultimate Guide to Egg Freezing: Everything You Need to Know

Discover how egg freezing can help preserve your fertility for future family planning. Learn about the process, success rates, and what to expect in this ultimate guide.

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All of our blog posts are written, edited, or produced by the London Women’s Clinic Content Team. This is a collaboration between our expert writers, health editors, and the leading researchers and senior doctors at our Harley Street clinic.

Key Takeaways

  • Egg freezing is a process where a woman's eggs are extracted, frozen, and stored for future use.
  • Women may consider egg freezing for reasons such as preserving fertility, medical conditions, or personal choice.
  • Before undergoing egg freezing, it's important to prepare both physically and emotionally for the process.
  • The egg freezing procedure involves hormone injections, egg retrieval, and freezing the eggs for storage.
  • Potential risks and considerations of egg freezing include side effects from hormone injections and the possibility of unsuccessful thawing or conception.

Understanding Egg Freezing: The Basics

Egg freezing, also known as oocyte cryopreservation, is a medical procedure that allows women to preserve their fertility by storing their eggs for future use. This process involves the extraction, freezing, and storage of a woman's eggs, which can then be thawed and used for in vitro fertilisation (IVF) at a later date. The purpose of egg freezing is to provide women with the opportunity to delay childbearing for personal or medical reasons, while still preserving their fertility potential. Advances in egg freezing technology have made the procedure more accessible and effective.

The history of egg freezing can be traced back to the 1980s, when the first successful human egg freezing and thawing was reported. Over the years, advancements in cryopreservation technology and techniques have significantly improved egg freezing success rates, making it a more viable and accessible option for women. Today, egg freezing is considered a reliable and well-established fertility preservation method, offering women greater control over their reproductive choices. Many women consider egg freezing as a way to delay pregnancy while pursuing their careers or personal goals.

Reasons to Consider Egg Freezing

One of the primary reasons women choose to freeze their eggs is to delay childbearing for personal or career-related reasons. Egg freezing offers women the opportunity to preserve their fertility for future family planning. As women age, their fertility naturally declines, and the risk of age-related fertility issues, such as decreased egg quality and quantity, increases. By freezing their eggs at a younger age, women can preserve their fertility potential and have the option to use their frozen eggs for future family planning.

Another common reason for egg freezing is to preserve fertility due to medical conditions or treatments that may impact a woman's reproductive system. For example, women undergoing cancer treatments, such as chemotherapy or radiation therapy, may opt to freeze their eggs before starting their treatment, as these therapies can potentially damage or destroy the ovaries and eggs. Egg freezing provides these women with the opportunity to have biological children in the future, even if their fertility is compromised by their medical condition or treatment. The decision to undergo egg freezing should be discussed with a fertility specialist to understand the potential benefits and risks.

Concerns about age-related fertility decline are also a significant factor driving the decision to freeze eggs. As women age, the quality and quantity of their eggs decrease, making it more challenging to conceive naturally or through assisted reproductive technologies. By freezing their eggs at a younger age, women can increase their chances of having a successful pregnancy in the future, even if they choose to delay starting a family. Egg freezing is becoming an increasingly popular option for women who want to extend their reproductive choices.

Preparing for the Egg Freezing Process

The initial stage of the egg cryopreservation (or egg freezing) process involves a meeting with a fertility expert. The specialist will gauge not only the woman's fertility health but also her overall wellness, to check if she is a good candidate for the egg freezing procedure. This typically relies upon a physical exam, several key blood tests to evaluate the woman's hormone levels and potential fertility, and an ultrasound to study the anatomy and health of the woman's ovaries. After these assessments, if the fertility specialist gives the green light, the woman can move forward toward the next step in the egg freezing process. All egg freezing in the UK is regulated by the HFEA.

Ovarian stimulation is the first step that a woman must go through when she is preparing to undergo in vitro fertilization (IVF). The woman must take hormones to stimulate her ovaries to produce several eggs concurrently. The woman takes them for 10 days on average.

The extraction of eggs is usually carried out with the woman under sedation or general anesthesia, ensuring both comfort and safety. Once the eggs are removed, they are quickly frozen and stored for use at a later time.

The Egg Freezing Procedure: What to Expect

The basic premise of the egg freezing procedure is to obtain mature eggs from a woman's ovaries, and this is done through a process called egg retrieval. To accomplish this, fertility specialists use a technique very similar to what fertility specialists have used for years—the process of in vitro fertilization or IVF. With IVF, eggs are gathered from a woman's ovaries, and then the eggs are fertilized and grown in a laboratory. The finished embryos are then transferred to the woman's uterus. However, in the case of egg freezing, the harvested eggs are not immediately fertilized but instead are frozen for future use.

Typically, a woman will feel just slight discomfort or cramping when the eggs are harvested, and the actual procedure takes under half an hour. The eggs are vitrified (cooled very rapidly) to a sufficiently low temperature that they should remain stable for a very long time.

Potential Risks and Considerations

Although egg freezing is largely a safe and routine procedure, there are some potential risks. The most frequent side effect happens to be ovarian hyperstimulation syndrome (OHSS), which occurs as a result of the fertility medications used to 'turn on' the ovaries and get them to produce eggs. Most of the time, suitable preemptive measures are taken and the specialist keeps a close enough eye on the patient that any developing situation is soon remedied, but it is good to know what is at stake for your health if you go through this procedure.

Costs and Financial Implications

The cost of egg freezing can be a significant consideration for many women. The overall cost of the procedure can vary widely depending on the fertility clinic, the location, and the individual's specific medical needs. Generally, egg freezing costs, including the initial consultation, medication, and the egg retrieval procedure, can range from £5,000 to £10,000 or more in the UK.

In addition to the initial cost of the egg freezing procedure, there are also ongoing costs associated with the long-term storage of the frozen eggs. These storage fees can range from a few hundred pounds to several hundred pounds per year, depending on the fertility clinic and the duration of storage.

When considering the financial implications of egg freezing, it's crucial for women to carefully research and compare the costs and coverage options available to them. Consulting with a fertility specialist and a financial advisor can help individuals make an informed decision and plan for the long-term costs associated with egg freezing.

Utilising Your Frozen Eggs for Conception

Conception using frozen eggs requires a well-choreographed series of steps, starting with egg thawing and preparation. After the eggs have been thawed, they are fertilized with sperm using in vitro fertilization. This process injects a single sperm into each of the mature eggs, with the fertilized eggs then cultured for several days before being transferred to the woman’s uterus. A major study published by the London Women's Clinic has shown that egg freezing effectiveness is equal to that done with fresh eggs.

Once the eggs have been fertilized, the resulting embryos are carefully monitored and cultured in the laboratory for several days. When the embryos have reached the appropriate developmental stage, one or more of them are selected for transfer back to the woman's uterus in hopes of achieving the successful establishment of a pregnancy.

Using cryopreserved eggs for conception can result in a viable pregnancy but is not guaranteed. Depending on several circumstances, the resulting pregnancy may more closely resemble naturally occurring pregnancies seen in younger women. The age of a woman at the time she harvested her eggs is, by far, the most influential factor in predicting the outcome associated with the use of those eggs, either frozen or unfrozen.

Using frozen eggs for conception may require extra thought and planning because of several associated factors. One is the potential necessity of donor sperm, especially in cases where male partners are not available. Another is the probable need to create more than one embryo, as studies suggest that a single embryo transfer results in a far lower pregnancy rate than transferring multiple embryos. Finally, the very act of freezing and thawing eggs (and any resulting embryos) carries with it certain unknowns that can only be understood by physicians familiar with the latest research and developments in human reproductive technology.

FAQs

What is egg freezing and how does it work?

Egg freezing, also known as oocyte cryopreservation, is a process in which a woman's mature egg cells are extracted, frozen, and stored for future use. The freezing process involves several key steps, including egg retrieval, where eggs are collected from the ovaries, and the actual freezing, which is typically performed using a technique called vitrification. This rapid freezing method helps to preserve the integrity of the eggs, ensuring that they remain viable for future fertilization.

Why might someone choose to freeze their eggs?

Individuals may choose to freeze their eggs for various reasons, including the desire to delay fertility until they are ready to start a family, personal or career-related goals, or medical reasons such as the need for fertility treatment due to health issues. Social egg freezing has gained popularity as it allows women to take control of their reproductive choices, preserving their ability to have children at a later date.

What is the typical egg freezing cost?

The egg freezing cost can vary significantly depending on several factors, including the location of the fertility clinic, the specifics of the treatment plan, and any additional services such as medication and storage fees. On average, the total cost for one egg freezing cycle can range from £5,000 to £10,000.

What are the success rates associated with egg freezing?

The success rates of egg freezing depend on various factors, including the age of the woman at the time of egg collection and the quality of the eggs retrieved. Generally, younger women, particularly those under the age of 35, have higher egg freezing success rates.

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