4.5

Fertility Treatments

Implantation Clinic

Here to help when starting again feels hard. We provide specialised care for patients after previous unexplained failures, combining advanced immunology diagnostics with personalised treatment to maximise your chances of pregnancy.

What is the Implantation Clinic?

The Implantation Clinic at London Women’s Clinic is designed for patients who have experienced failed embryo transfers despite good-quality embryos. Using advanced validated techniques, we study the immune environment of the womb lining to better understand factors that may affect implantation. Research* shows that endometrial immune profiling can identify key factors contributing to recurrent implantation failure, helping guide personalised treatment.

  • Using a range of advanced immune profiling tests, the clinic identifies factors that may prevent embryo implantation.
  • Based on results, we tailor treatment to address immune imbalances, with interventions aimed at restoring immunological balance in the endometrium.

The tests involve an out-patient procedure and our team provides support and guidance throughout the process to ensure your comfort and understanding.

Who is the Implantation Clinic suitable for?

The Implantation Clinic is designed for patients experiencing repeated embryo transfer failures with good quality blastocysts, who are seeking personalised insight into why implantation has not occurred.

It can be suitable for individuals who have undergone:

  • IVF or ICSI
  • IVF or ICSI with Preimplantation Genetic Testing (PGT-A)
  • Egg donation cycles

Our team supports you with tailored assessments to help understand the factors affecting implantation and guide the next steps in your fertility journey.

women talking and smiling

How does the Implantation Clinic work?

The Implantation Clinic is designed to better understand the environment in which implantation takes place. By carefully assessing your endometrium during a controlled cycle, our specialists can develop a personalised treatment plan based on your individual results.

Successful implantation depends not only on embryo quality but also on the health and readiness of the womb lining. Research from Dr Mona Rahmati and Professor Nick Macklon shows that advanced endometrial testing can identify factors affecting implantation, helping to guide personalised treatment plans rather than relying on trial-and-error approaches.*

*Endometrial immune assessment in patients with a history of previous euploid blastocyst failure.

Step 1

Initial appointment with a specialist, via referral or self-referral, to review your history and eligibility.

Step 2

You will be prepared in a medicated “mock” HRT cycle for endometrial testing. During this stage, you’ll take prescribed medication to recreate the natural hormonal environment and ensure your womb lining is ready for the biopsy.

Step 3

Conducted during a specific time in your cycle, including:

  • Hormonal blood tests
  • Pelvic ultrasound scans
  • Endometrial biopsy (a small sample of the womb lining is collected and sent for analysis)

Important note: For optimal results, your frozen embryo transfer (FET) should take place within six months of your endometrial biopsy.

Step 4

Laboratory analysis identifies potential causes of implantation failure and guides treatment recommendations.

Step 5

Results reviewed with your specialist to set a personalised treatment plan. In rare cases, tests may need to be repeated.

Meet the specialists behind the Implantation Clinic

The Implantation Clinic concept was pioneered by Professor Nick Macklon, a Senior Consultant Gynaecologist and IVF Specialist, and Group Medical Director whose decades of experience in reproductive medicine have shaped the understanding of human embryo implantation worldwide.

With over 250 published studies and numerous international awards, his research continues to inform innovative approaches to IVF and reproductive care. Today, his expertise is a cornerstone of the LWC programme, ensuring patients benefit from the latest scientific insights.

Headshot of Professor Nick Macklon
Professor Nick Macklon
Headshot of Dr Mona Rahmati
Dr Mona Rahmati

The Implantation Clinic also draws on the specialist skills of Dr Mona Rahmati, a Senior Consultant Gynaecologist and IVF Specialist with a PhD in reproductive immunology.

She focuses on helping patients with recurrent implantation failure, applying cutting-edge immune profiling tests to tailor treatment and restore balance in the endometrium.

Studies show that patients attending the clinic have achieved pregnancy rates of around 40%, reflecting the clinic’s personalised, evidence-based approach.

Implantation Clinic Success in Numbers

148 babies born following personalised frozen embryo transfer

Since the Implantation Clinic was established in 2018, we have analysed a total of 547 endometrial biopsies, resulting in 484 personalised frozen embryo transfers.

Previous fertility history:

  • 54% had previous failures with embryos created using their own eggs
  • 21% had previous failures with embryos created using donor eggs
  • 25% had previous failures with both own and donor eggs

OUTCOMES SO FAR

  • 148 babies born following personalised frozen embryo transfer within the six-month test validity window
  • 20 ongoing pregnancies currently underway
  • Patients include 73% heterosexual couples and 27% same-sex couples or single individuals using donor sperm

Our personalised approach maximises the chances of success, even after repeated embryo transfer failures.

Want to learn more? Explore our success rates page to see the latest outcomes.

How much does Implantation Clinic testing cost?

Understanding the costs involved is an important step. We aim to provide clear, transparent pricing so you know what to expect from the start.

For a full breakdown of costs and what’s included in our ICSI treatment plans, please get in touch with our team.

Implantation Clinic Testing Prices

Costs start from

Implantation Clinic Package for Internal Patients £1,985.00
Implantation Clinic Package for External Patients £2,555.00
Mock Embryo Transfer £200.00
Initial Consultation for External Patient £225.00
Microbiome Test for Implantation £685.00
‘I honestly cannot fault Kind IVF. From start to finish, I have been so incredibly impressed with the care, compassion and professionalism shown by the entire team. Going through IVF can be such an emotional and overwhelming journey, but they have made the whole experience feel so much more reassuring and positive. Every step of the way, I have felt cared for, listened to and supported. The team have been amazing at answering questions, putting my mind at ease and making sure I felt comfortable throughout the process. You can really tell how much they care about their patients, and that makes such a huge difference during a journey that can be so personal and emotional. I am so grateful to everyone at Kind IVF for everything they have done for us. Choosing them has been one of the best decisions we have made, and I genuinely couldn’t recommend them enough to anyone considering IVF. The standard of care has been outstanding, and I cannot thank them enough for helping us on this journey. ❤️ Thank you, Kind IVF, for being so amazing!’

Georgia Burt

22 October 2026, LWC Tunbridge Wells

‘I highly recommend the London Women's Clinic Brentwood. The staff were very supportive, patient, and always available to answer questions. They guided me through an emotional process with clear explanations and genuine care. The staff were always available and happy to help.’

S Begum

21 October 2026, LWC Brentwood

‘Choosing an IVF clinic is such a big decision and I'm so incredibly glad that we chose this one. IVF can be such an emotional and overwhelming journey but having a clinic that offers so much support and genuinely cares for you makes such a difference. The care and kindness that we have received has been exceptional. We can't thank LWC Brentwood enough ❤️’

Laura Keary

21 October 2026, LWC Brentwood

‘I honestly can’t thank London Women’s Clinic enough for helping me achieve my lifelong dream of becoming a mum. It wasn’t an easy journey, but the team were absolutely fantastic and supported me every step of the way. Their kindness, care and reassurance made such a difference during what was a really emotional and challenging time. I always felt supported and in safe hands. A special thank you to Carla, Ana-Maria and Dr Goswami. You have all been absolutely fantastic and I am so grateful for everything you have done for me. I’ll never forget the support and care you have shown me during such an important and emotional journey. Thank you all from the bottom of my heart for helping me achieve something I have wanted for as long as I can remember. It means more to me than words can say. I would recommend London Women’s Clinic to anyone going through their own fertility journey.’

Sarah

21 October 2026, LWC Harrow

‘We started our treatment in July, and I have had a very positive experience with this clinic. Lorraine on reception especially made me feel like nothing was too much trouble and always knew me by name which is such a nice personal touch, especially at such a sensitive time. Along with Dr Safwat Ashour he always recommended the best treatment for us and just had such a kind caring attitude towards us while explaining our options and being very honest with us too. One of the nurses (so sorry I can’t remember your name) she only recently started in July and I felt so at home with her and cared for. To finish off we are currently pregnant with our IVF miracle all thanks you this clinic. Thank you all so much, no thanks would ever be enough for the gift you have given us!’

Sophie Jay

21 October 2026, LWC Darlington

‘Very professional and very welcoming, and very clean I was given time to feel relaxed and I didn't feel like I had to rush this made me feel very comfortable.’

Ryan Harmer

21 October 2026, LWC Brighton

‘My wife and I have had a brilliant experience with LWC throughout our fertility journey. We always felt listened to, supported, and in control of the decisions we were making. Our PCC Suzanna, Dr Verstraete, and the nursing team were consistently friendly, responsive, and knowledgeable, which made navigating the shared motherhood process feel so much easier. We’re incredibly grateful for the care and support we received.’

Megan Nelkon

20 October 2026, LWC Harley Street

‘I’ve had a great experience with the clinic so far. From the very beginning, I’ve felt incredibly well cared for and supported throughout my egg freezing journey. Daenira on reception is always so lovely, welcoming and helpful, and Liv, my nurse, has been fantastic! She’s made me feel comfortable, reassured and well looked after at every step. Dr Wade has also been absolutely brilliant and I have complete confidence in the care and guidance I’ve received. I would highly recommend this clinic to anybody considering egg freezing.’

Saffy

20 October 2026, LWC Oxford

‘The most amazing experience with the clinic from start to end Nothing is to much for them They will answer every Question Worry or concern no matter how big or small, My experience and care they have shown in one of the hardest times and most worrying experiences they were there every single step of the way, I honestly couldn’t thank every member I’ve dealt with anymore and would recommend this clinic to anyone thinking about it , hardest decision but best decision every made and all the staff here made this possible for me you are all amazing caring people And I thank you from the bottom of my heart 🙏🏼🩷’

Stephanie

18 October 2026, LWC Brentwood

‘I truly feel blessed and thankful to God that we are in such a wonderful place and in such caring hands during one of the most precious journeys of our lives. The clinic has been outstanding throughout my treatment, making the entire journey feel as smooth as possible. The whole team at the Brentwood clinic is absolutely amazing, everyone is so warm, welcoming and supportive. The treatment has been incredible so far, and we are extremely satisfied with the care, support, and overall service we have received throughout our journey. Fingers crossed, I truly believe that the best news is just around the corner! ❤️🤞 I would wholeheartedly recommend Brentwood clinic for the care and support they provide in parenthood journey.’

Harika

14 October 2026, LWC Brentwood

‘London Women’s Clinic, Reading were fantastic and Nurse Nicky was such a supportive and reassuring professional. Thank you for journeying with me Nicky!’

Sope Adekola

14 October 2026, LWC Reading

‘Where to start… Fertility treatment is the last thing any of us expect to need. But if you find yourself on this journey, Brentwood London Women’s Clinic is where you want to be. Carina’s warm welcome sets the tone the moment you arrive, and every single nurse is wonderful, kind, calm, and reassuring. It’s a complicated and sometimes difficult road, but they walk it beside you. We’ve experienced both joy and heartache here, and through every moment we’ve felt cared for and supported. They truly get to know you, and the care feels personal and bespoke. Today we have our precious 3-year-old, and we will forever be thankful to this amazing team. They are everything you could hope for kind, knowledgeable, and genuinely there for you. We couldn’t recommend them more.’

Sarah Tidey

13 October 2026, LWC Brentwood

‘We honestly can’t thank London Women’s Clinic in Brentwood enough for everything they have done and continue to do for us. They helped us create our now 3 year old, and we are incredibly grateful to be back with them on our journey to hopefully have another little one. Angela and Katie are truly incredible nurses. They go above and beyond to make you feel comfortable, listened to and supported every step of the way. They take the time to explain the process, answer any questions and put your mind at ease, making what can sometimes be an overwhelming and emotional journey feel that little bit easier. It means so much to be cared for by people who genuinely seem to care about you and your family, rather than just seeing you as another patient. Their kindness, compassion and reassurance make such a difference, and we feel very lucky to have them supporting us again. We will always be grateful to London Women’s Clinic for helping us bring our little girl into the world, and we have every hope that they will help us grow our family once more. We couldn’t recommend the team highly enough. Thank you, Angela, Katie and everyone at the Brentwood clinic, for being such a special part of our journey. ❤️ Also a special mention for the smiley face in the reception. Carina, you are great!!’

bethan philp

13 October 2026, LWC Brentwood

‘Came here after my treatment at LWC Darlington as I needed to be part of the failed implantation team. The care and communication was second to none. It was everything and more, no question to my coordinator was never too much. They were extremely accommodating when I had to travel from up north multiple times and were always happy to let me have my then 2 year old son come to monitoring appointments. I’m grateful for their expertise in failed implantation as my 3rd egg collection was successful and my fresh transfer worked first time & I’ve just gave birth to my second LWC baby in September 2026. Would always recommend LWC - especially London Bridge / Harley Street.’

Jeni J

13 October 2026, LWC London Bridge

‘Great experience. Very kind and supportive.’

Jesylin Luka

12 October 2026, LWC Reading

‘My experience with London Women's Clinic Brighton has been wonderful so far. The staff are kind and patient, as well as exceptionally knowledgeable. I have had all my questions answered (and have been encouraged to ask more whenever!), and I feel assured that I'm receiving transparent, evidence-based advice.’

Jess Smith

12 October 2026, LWC Brighton

‘Excellent service, highly recommend!’

Lenka Kalafutova

10 October 2026, LWC Tunbridge Wells

‘Lovely people. Truly!’

Eve Reiser

8 October 2026, LWC Reading

‘My experience was positive throughout. The team at the clinic was friendly at every visit. Suzanna was always very responsive and kind and happy to answer any questions. Dr Verstraete was always empathetic and knowledgeable! Most importantly: the outcome is a healthy baby :)’

Mir

8 October 2026, LWC Harley Street

‘Thank you so much Dr Naware, Linda and Emmanuella’

Moyo T

7 October 2026, LWC London Bridge

4.5

FAQs about the Implantation Clinic

In some cases, no issues are identified. Rarely, tests may need to be repeated to provide further insight.

Laboratory analysis typically takes 4–5 weeks, followed by a consultation to discuss your personalised treatment plan.

Most patients experience only mild discomfort, similar to a smear test. Our team supports you throughout to ensure you feel comfortable and informed.

If you’ve had one or more failed embryo transfers despite good quality embryos, our doctors can review your history and discuss whether personalised endometrial testing could provide insight.

Let us help you try again

Book your consultation at the Implantation Clinic to explore why previous embryo transfers may not have succeeded. We will review your history, conduct any necessary assessments and create a personalised treatment plan tailored to your reproductive journey.