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4.5

Fertility Treatments

Implantation Clinic

Here to help when starting again feels hard. We provide specialised care for patients after previous unexplained failures, combining advanced immunology diagnostics with personalised treatment to maximise your chances of pregnancy.

What is the Implantation Clinic?

The Implantation Clinic at London Women’s Clinic is designed for patients who have experienced failed embryo transfers despite good-quality embryos. Using advanced validated techniques, we study the immune environment of the womb lining to better understand factors that may affect implantation. Research* shows that endometrial immune profiling can identify key factors contributing to recurrent implantation failure, helping guide personalised treatment.

  • Using a range of advanced immune profiling tests, the clinic identifies factors that may prevent embryo implantation.
  • Based on results, we tailor treatment to address immune imbalances, with interventions aimed at restoring immunological balance in the endometrium.

The tests involve an out-patient procedure and our team provides support and guidance throughout the process to ensure your comfort and understanding.

Who is the Implantation Clinic suitable for?

The Implantation Clinic is designed for patients experiencing repeated embryo transfer failures with good quality blastocysts, who are seeking personalised insight into why implantation has not occurred.

It can be suitable for individuals who have undergone:

  • IVF or ICSI
  • IVF or ICSI with Preimplantation Genetic Testing (PGT-A)
  • Egg donation cycles

Our team supports you with tailored assessments to help understand the factors affecting implantation and guide the next steps in your fertility journey.

women talking and smiling

How does the Implantation Clinic work?

The Implantation Clinic is designed to better understand the environment in which implantation takes place. By carefully assessing your endometrium during a controlled cycle, our specialists can develop a personalised treatment plan based on your individual results.

Successful implantation depends not only on embryo quality but also on the health and readiness of the womb lining. Research from Dr Mona Rahmati and Professor Nick Macklon shows that advanced endometrial testing can identify factors affecting implantation, helping to guide personalised treatment plans rather than relying on trial-and-error approaches.*

*Endometrial immune assessment in patients with a history of previous euploid blastocyst failure.

Step 1

Initial appointment with a specialist, via referral or self-referral, to review your history and eligibility.

Step 2

You will be prepared in a medicated “mock” HRT cycle for endometrial testing. During this stage, you’ll take prescribed medication to recreate the natural hormonal environment and ensure your womb lining is ready for the biopsy.

Step 3

Conducted during a specific time in your cycle, including:

  • Hormonal blood tests
  • Pelvic ultrasound scans
  • Endometrial biopsy (a small sample of the womb lining is collected and sent for analysis)

Important note: For optimal results, your frozen embryo transfer (FET) should take place within six months of your endometrial biopsy.

Step 4

Laboratory analysis identifies potential causes of implantation failure and guides treatment recommendations.

Step 5

Results reviewed with your specialist to set a personalised treatment plan. In rare cases, tests may need to be repeated.

Meet the specialists behind the Implantation Clinic

The Implantation Clinic concept was pioneered by Professor Nick Macklon, a Senior Consultant Gynaecologist and IVF Specialist, and Group Medical Director whose decades of experience in reproductive medicine have shaped the understanding of human embryo implantation worldwide.

With over 250 published studies and numerous international awards, his research continues to inform innovative approaches to IVF and reproductive care. Today, his expertise is a cornerstone of the LWC programme, ensuring patients benefit from the latest scientific insights.

Headshot of Professor Nick Macklon
Professor Nick Macklon
Headshot of Dr Mona Rahmati
Dr Mona Rahmati

The Implantation Clinic also draws on the specialist skills of Dr Mona Rahmati, a Senior Consultant Gynaecologist and IVF Specialist with a PhD in reproductive immunology.

She focuses on helping patients with recurrent implantation failure, applying cutting-edge immune profiling tests to tailor treatment and restore balance in the endometrium.

Studies show that patients attending the clinic have achieved pregnancy rates of around 40%, reflecting the clinic’s personalised, evidence-based approach.

Implantation Clinic Success in Numbers

148 babies born following personalised frozen embryo transfer

Since the Implantation Clinic was established in 2018, we have analysed a total of 547 endometrial biopsies, resulting in 484 personalised frozen embryo transfers.

Previous fertility history:

  • 54% had previous failures with embryos created using their own eggs
  • 21% had previous failures with embryos created using donor eggs
  • 25% had previous failures with both own and donor eggs

OUTCOMES SO FAR

  • 148 babies born following personalised frozen embryo transfer within the six-month test validity window
  • 20 ongoing pregnancies currently underway
  • Patients include 73% heterosexual couples and 27% same-sex couples or single individuals using donor sperm

Our personalised approach maximises the chances of success, even after repeated embryo transfer failures.

Want to learn more? Explore our success rates page to see the latest outcomes.

How much does Implantation Clinic testing cost?

Understanding the costs involved is an important step. We aim to provide clear, transparent pricing so you know what to expect from the start.

For a full breakdown of costs and what’s included in our ICSI treatment plans, please get in touch with our team.

Implantation Clinic Testing Prices

Costs start from

Implantation Clinic Package for Internal Patients £1,985.00
Implantation Clinic Package for External Patients £2,555.00
Mock Embryo Transfer £200.00
Initial Consultation for External Patient £225.00
Microbiome Test for Implantation £685.00
‘We have two beautiful children - our family wouldn't exist without LWC Brentwood.<br><br>Can't recommend them highly enough; IVF is an emotional rollercoaster regardless of your journey and we were supported at every step.<br><br>Pricing is transparent and easy to understand, with payment plans available that made accessing any treatment and medication very flexible and affordable.<br><br>The clinic became such a part of our lives for that short time, the care and support is so important and LWC Brentwood were brilliant. Maybe we will see them again for number 3!’

Victoria Hayman

10 November 2026, LWC Brentwood

‘I would like to express my heartfelt thanks to the entire team for supporting me throughout my IVF journey.<br><br>I am delighted to share that I had a positive pregnancy test following my very first IVF cycle fresh embryo transfer, and I am now 9 weeks pregnant!<br><br>The staff at the LWC Colchester satellite clinic are very supportive, approachable and always do their best to help you at every stage of the journey. I would definitely recommend LWC Colchester to anyone considering fertility treatment.<br><br>A special thank you to Dr Timea Kovats, a highly experienced, knowledgeable and to the wonderful staff Jackie, Annette, Tracey.<br><br>Their excellent guidance, expertise, care and supportive approach played a significant role in making my first IVF cycle successful. I am truly grateful for their dedication, encouragement and support throughout this journey.<br><br>I am equally grateful to all the staff at Colchester satellite clinic and the London main clinic for their care and support throughout the entire process.<br><br>Thank you once again for helping us achieve such a special milestone in our lives. We will always be grateful for your support! ❤️’

jigu

10 November 2026, LWC Colchester

‘Friendly, experienced and professional team. Supported throughout the entire process and would highly recommend.’

Mizzee West

10 November 2026, LWC Brighton

‘The nursing team are so friendly and so supportive. Made everything so much better and easier to go through egg freezing.’

Megan Godber

10 November 2026, LWC Brighton

‘We had a great experience as the team here are very knowledgeable and caring and they made us feel taken care of throughout! Big shout out to Rute & Trianni for their care and support 😊’

Chiamaka Nelson

9 November 2026, LWC Cambridge

‘The team here are very kind and helpful and made the journey completely painless! They kept us informed throughout the process and were always responsive when we had questioned’

Aruna Nelson

9 November 2026, LWC Cambridge

‘They've given us wonderful service very easy to be around. Very good communication, and very good at helping us out with everything they've done so far.’

Jessica Norman

9 November 2026, LWC Oxford

‘We had a fantastic experience with LWC, Dr Rimington’s passion and expertise were second to none and we strongly believe that he is the reason for our success. All the staff were lovely, helpful and kind - we will definitely use LWC again’

Hannah Hale

9 November 2026, LWC Brighton

‘I honestly cannot recommend this fertility clinic highly enough. From the very beginning, the care, compassion and support we received were absolutely exceptional.<br><br>Going through fertility treatment is an incredibly emotional journey, with so many ups and downs, but the team made us feel supported, listened to and genuinely cared for every step of the way. Nothing ever felt like too much trouble, and every member of staff we encountered was kind, understanding, professional and reassuring.<br><br>What really stood out was how personal the experience felt. We never felt like just another number. The team took the time to answer our questions, put our minds at ease and guide us through what can sometimes feel like an overwhelming process.<br><br>We are incredibly grateful for everything they have done for us and will never forget the part they have played in helping us grow our family. We now have our little miracles, and we couldn't be more thankful.<br><br>If you're considering fertility treatment, I would wholeheartedly recommend LWC. Thank you from the bottom of our hearts for helping make our dream come true! ❤️’

Emma Hayman

8 November 2026, LWC Brentwood

‘Had a really positive experience visiting the Oxford Clinic. Nurse Manager Liv, took time to make me us feel at ease and explained how the appointment will go. Thank you!’

Kinga Arcana-Jones

7 November 2026, LWC Oxford

‘Everyone my partner and I have interacted with at the Oxford clinic has been warm, friendly and knowledgeable. They’ve really helped make a very daunting process easier to go through and I’m very glad we chose this clinic!’

Jess Palmer

5 November 2026, LWC Oxford

‘Very friendly staff and a lovely inclusive environment, had a wonderful experience here. Highly recommend for anyone looking at fertility preservation.’

T Ilagan

5 November 2026, LWC Oxford

‘As an LGBTQ couple we found LWC Colchester incredibly supportive, no question was too much. They were friendly and welcoming, with modern facilities, and made your journey feel very personalised. We would highly recommend them for your fertility journey.’

Jasmine Colman

5 November 2026, LWC Colchester

‘A massive thank you to Dom and Dr Vasquez for all of their help throughout the process!’

James Purcell

5 November 2026, LWC Tunbridge Wells

‘Me and my husband can’t thank everyone at London Women’s Clinic enough for all the care and support throughout our recent treatment. Everything went really well, and we are so grateful to all the doctors and the entire team for looking after me. A special thank you to Mimi, Dr Barbara, Caroline, Trina and Elena from Embryology team and the Theatre Team - Rose, Martin and Amy F. Everyone was so kind, helpful and reassuring, and it really made a difference. Thank you all for everything. ♥️♥️♥️♥️♥️’

IsadelandCyril

4 November 2026, LWC Harley Street

‘I would like to express my heartfelt gratitude and appreciation to the entire team who supported us throughout our IVF treatment. ❤️<br><br>A special thank you to Ana-Maria,our nurse, for her kindness, patience, compassion and professionalism. She was always so caring, understanding and supportive, making us feel reassured and comfortable during such an emotional and challenging journey.<br><br>We would also like to thank Dr Gill from the bottom of our hearts for his professionalism, dedication, expertise and the confidence he gave us throughout the entire process.<br><br>IVF is not just a medical treatment; it is an emotional journey filled with hope, challenges and many feelings. Having such wonderful people by our side made everything so much easier.<br><br>Thank you for your care, support and dedication. We truly appreciate everything you have done for us and would wholeheartedly recommend you to anyone beginning their IVF journey.<br><br>Thank you for being part of our journey! ❤️’

Alexandru Predescu

3 November 2026, LWC Harrow

‘I would like to express my heartfelt gratitude and appreciation to the entire team who supported us throughout our IVF treatment. ❤️<br><br>A special thank you to Ana-Maria,our nurse, for her kindness, patience, compassion and professionalism. She was always so caring, understanding and supportive, making us feel reassured and comfortable during such an emotional and challenging journey.<br><br>We would also like to thank Dr Gill from the bottom of our hearts for his professionalism, dedication, expertise and the confidence he gave us throughout the entire process.<br><br>IVF is not just a medical treatment; it is an emotional journey filled with hope, challenges and many feelings. Having such wonderful people by our side made everything so much easier.<br><br>Thank you for your care, support and dedication. We truly appreciate everything you have done for us and would wholeheartedly recommend you to anyone beginning their IVF journey.<br><br>Thank you for being part of our journey! ❤️’

Mihaela-Clemansa Predescu

3 November 2026, LWC Harrow

‘Simply Brilliant .’

Ramachandran Jeyamohan

3 November 2026, LWC Colchester

‘I feel so blessed and grateful to have been under the lovely nurse Katie and Dr Kovats’s care. Everyone I encountered in the clinic on or off line was friendly, reassuring, thoughtful, and patient with me.<br><br>I could feel the genuine care from Katie and Dr Kovats. I feel very reassured knowing they'd be there with me every step of the way; it is a great relief to have medical professionals like them on my side. They listened attentively, were reassuring, explained what I need to know thoroughly and were very approachable.<br><br>Thank you to Carina, the friendly clinic coordinator, for always answering my emails promptly and being so helpful with all the questions I threw at her.<br><br>Also, to the lovely staff member with blonde hair (I’m so sorry I forgot your name!) who did the ultrasound scan, thank you for being so attentive and making me feel relaxed.<br><br>The clinic has a calm, relaxing vibe and is very clean.<br><br>I have had a wonderful experience with the clinic and would highly recommend the team to anyone on their fertility journey!’

T Yang

3 November 2026, LWC Brentwood

‘We have used London Women's Clinic twice in the last two years for successful egg retrieval and two subsequent frozen embryo transfers. We have always been met with care, compassion and a personal approach. Every step from the initial consultation right through to the 7 week scan has been professional and polite, always accommodating our needs and timings. We can't thank the team enough for giving us such support towards creating our family.’

Lucy Richards

2 November 2026, LWC Tunbridge Wells

4.5

FAQs about the Implantation Clinic

In some cases, no issues are identified. Rarely, tests may need to be repeated to provide further insight.

Laboratory analysis typically takes 4–5 weeks, followed by a consultation to discuss your personalised treatment plan.

Most patients experience only mild discomfort, similar to a smear test. Our team supports you throughout to ensure you feel comfortable and informed.

If you’ve had one or more failed embryo transfers despite good quality embryos, our doctors can review your history and discuss whether personalised endometrial testing could provide insight.

Let us help you try again

Book your consultation at the Implantation Clinic to explore why previous embryo transfers may not have succeeded. We will review your history, conduct any necessary assessments and create a personalised treatment plan tailored to your reproductive journey.