A recent abstract accepted for Fertility 2026 provides valuable insights into how Pre-implantation Genetic Testing for Aneuploidy (PGT-A) can improve IVF outcomes.

How PGT-A Can Impact IVF Success 

Age plays a significant role in IVF success. As women get older, the likelihood of genetic abnormalities in eggs increases, which can make achieving a healthy pregnancy more challenging. PGT-A allows clinicians to screen embryos for chromosomal abnormalities before implantation, helping identify those with the highest potential for a live birth.

The study, a single-centre analysis of 13,000 frozen embryo transfers, highlights the impact of PGT-A across different age groups:

• For patients under 38, PGT-A increased the live birth rate by 15%.

• For patients over 40, the benefit was even greater, with nearly 30% higher live birth rates.

• Across all patients, advanced analysis suggested that PGT-A could almost double the odds of a live birth compared to IVF without PGT-A.

These findings reinforce what many fertility specialists have observed: PGT-A can be a powerful tool for improving IVF outcomes, particularly for older patients. For prospective parents, it provides important guidance when making informed family-building decisions.

As research continues to expand, studies like this offer reassurance that science is helping make IVF more effective, personalised, and successful for patients of all ages.

Study reference:

Al-Hashimi B, Linara-Demakakou E, Shah T, Lamanna G, Rahmati M, Summers M, Garratt J, Macklon N, Ahuja K. Evaluating the efficacy of PGT-A across maternal ages: Insights from 13,000 frozen embryo transfers. Abstract accepted for Fertility 2026.