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4.5

Fertility Treatments

Implantation Clinic

Here to help when starting again feels hard. We provide specialised care for patients after previous unexplained failures, combining advanced immunology diagnostics with personalised treatment to maximise your chances of pregnancy.

What is the Implantation Clinic?

The Implantation Clinic at London Women’s Clinic is designed for patients who have experienced failed embryo transfers despite good-quality embryos. Using advanced validated techniques, we study the immune environment of the womb lining to better understand factors that may affect implantation. Research* shows that endometrial immune profiling can identify key factors contributing to recurrent implantation failure, helping guide personalised treatment.

  • Using a range of advanced immune profiling tests, the clinic identifies factors that may prevent embryo implantation.
  • Based on results, we tailor treatment to address immune imbalances, with interventions aimed at restoring immunological balance in the endometrium.

The tests involve an out-patient procedure and our team provides support and guidance throughout the process to ensure your comfort and understanding.

Who is the Implantation Clinic suitable for?

The Implantation Clinic is designed for patients experiencing repeated embryo transfer failures with good quality blastocysts, who are seeking personalised insight into why implantation has not occurred.

It can be suitable for individuals who have undergone:

  • IVF or ICSI
  • IVF or ICSI with Preimplantation Genetic Testing (PGT-A)
  • Egg donation cycles

Our team supports you with tailored assessments to help understand the factors affecting implantation and guide the next steps in your fertility journey.

women talking and smiling

How does the Implantation Clinic work?

The Implantation Clinic is designed to better understand the environment in which implantation takes place. By carefully assessing your endometrium during a controlled cycle, our specialists can develop a personalised treatment plan based on your individual results.

Successful implantation depends not only on embryo quality but also on the health and readiness of the womb lining. Research from Dr Mona Rahmati and Professor Nick Macklon shows that advanced endometrial testing can identify factors affecting implantation, helping to guide personalised treatment plans rather than relying on trial-and-error approaches.*

*Endometrial immune assessment in patients with a history of previous euploid blastocyst failure.

Step 1

Initial appointment with a specialist, via referral or self-referral, to review your history and eligibility.

Step 2

You will be prepared in a medicated “mock” HRT cycle for endometrial testing. During this stage, you’ll take prescribed medication to recreate the natural hormonal environment and ensure your womb lining is ready for the biopsy.

Step 3

Conducted during a specific time in your cycle, including:

  • Hormonal blood tests
  • Pelvic ultrasound scans
  • Endometrial biopsy (a small sample of the womb lining is collected and sent for analysis)

Important note: For optimal results, your frozen embryo transfer (FET) should take place within six months of your endometrial biopsy.

Step 4

Laboratory analysis identifies potential causes of implantation failure and guides treatment recommendations.

Step 5

Results reviewed with your specialist to set a personalised treatment plan. In rare cases, tests may need to be repeated.

Meet the specialists behind the Implantation Clinic

The Implantation Clinic concept was pioneered by Professor Nick Macklon, a Senior Consultant Gynaecologist and IVF Specialist, and Group Medical Director whose decades of experience in reproductive medicine have shaped the understanding of human embryo implantation worldwide.

With over 250 published studies and numerous international awards, his research continues to inform innovative approaches to IVF and reproductive care. Today, his expertise is a cornerstone of the LWC programme, ensuring patients benefit from the latest scientific insights.

Headshot of Professor Nick Macklon
Professor Nick Macklon
Headshot of Dr Mona Rahmati
Dr Mona Rahmati

The Implantation Clinic also draws on the specialist skills of Dr Mona Rahmati, a Senior Consultant Gynaecologist and IVF Specialist with a PhD in reproductive immunology.

She focuses on helping patients with recurrent implantation failure, applying cutting-edge immune profiling tests to tailor treatment and restore balance in the endometrium.

Studies show that patients attending the clinic have achieved pregnancy rates of around 40%, reflecting the clinic’s personalised, evidence-based approach.

Implantation Clinic Success in Numbers

148 babies born following personalised frozen embryo transfer

Since the Implantation Clinic was established in 2018, we have analysed a total of 547 endometrial biopsies, resulting in 484 personalised frozen embryo transfers.

Previous fertility history:

  • 54% had previous failures with embryos created using their own eggs
  • 21% had previous failures with embryos created using donor eggs
  • 25% had previous failures with both own and donor eggs

OUTCOMES SO FAR

  • 148 babies born following personalised frozen embryo transfer within the six-month test validity window
  • 20 ongoing pregnancies currently underway
  • Patients include 73% heterosexual couples and 27% same-sex couples or single individuals using donor sperm

Our personalised approach maximises the chances of success, even after repeated embryo transfer failures.

Want to learn more? Explore our success rates page to see the latest outcomes.

How much does Implantation Clinic testing cost?

Understanding the costs involved is an important step. We aim to provide clear, transparent pricing so you know what to expect from the start.

For a full breakdown of costs and what’s included in our ICSI treatment plans, please get in touch with our team.

Implantation Clinic Testing Prices

Costs start from

Implantation Clinic Package for Internal Patients £1,985.00
Implantation Clinic Package for External Patients £2,555.00
Mock Embryo Transfer £200.00
Initial Consultation for External Patient £225.00
Microbiome Test for Implantation £685.00
‘Me and my husband can’t thank everyone at London Women’s Clinic enough for all the care and support throughout our recent treatment. Everything went really well, and we are so grateful to all the doctors and the entire team for looking after me. A special thank you to Mimi, Dr Barbara, Caroline, the Theatre Team, Rose, Martin and Amy F. Everyone was so kind, helpful and reassuring, and it really made a difference. Thank you all for everything. ♥️♥️♥️♥️♥️’

IsadelandCyril

4 November 2026, LWC Harley Street

‘I would like to express my heartfelt gratitude and appreciation to the entire team who supported us throughout our IVF treatment. ❤️<br><br>A special thank you to Ana-Maria,our nurse, for her kindness, patience, compassion and professionalism. She was always so caring, understanding and supportive, making us feel reassured and comfortable during such an emotional and challenging journey.<br><br>We would also like to thank Dr Gill from the bottom of our hearts for his professionalism, dedication, expertise and the confidence he gave us throughout the entire process.<br><br>IVF is not just a medical treatment; it is an emotional journey filled with hope, challenges and many feelings. Having such wonderful people by our side made everything so much easier.<br><br>Thank you for your care, support and dedication. We truly appreciate everything you have done for us and would wholeheartedly recommend you to anyone beginning their IVF journey.<br><br>Thank you for being part of our journey! ❤️’

Alexandru Predescu

3 November 2026, LWC Harrow

‘I would like to express my heartfelt gratitude and appreciation to the entire team who supported us throughout our IVF treatment. ❤️<br><br>A special thank you to Ana-Maria,our nurse, for her kindness, patience, compassion and professionalism. She was always so caring, understanding and supportive, making us feel reassured and comfortable during such an emotional and challenging journey.<br><br>We would also like to thank Dr Gill from the bottom of our hearts for his professionalism, dedication, expertise and the confidence he gave us throughout the entire process.<br><br>IVF is not just a medical treatment; it is an emotional journey filled with hope, challenges and many feelings. Having such wonderful people by our side made everything so much easier.<br><br>Thank you for your care, support and dedication. We truly appreciate everything you have done for us and would wholeheartedly recommend you to anyone beginning their IVF journey.<br><br>Thank you for being part of our journey! ❤️’

Mihaela-Clemansa Predescu

3 November 2026, LWC Harrow

‘Simply Brilliant .’

Ramachandran Jeyamohan

3 November 2026, LWC Colchester

‘I feel so blessed and grateful to have been under the lovely nurse Katie and Dr Kovats’s care. Everyone I encountered in the clinic on or off line was friendly, reassuring, thoughtful, and patient with me.<br><br>I could feel the genuine care from Katie and Dr Kovats. I feel very reassured knowing they'd be there with me every step of the way; it is a great relief to have medical professionals like them on my side. They listened attentively, were reassuring, explained what I need to know thoroughly and were very approachable.<br><br>Thank you to Carina, the friendly clinic coordinator, for always answering my emails promptly and being so helpful with all the questions I threw at her.<br><br>Also, to the lovely staff member with blonde hair (I’m so sorry I forgot your name!) who did the ultrasound scan, thank you for being so attentive and making me feel relaxed.<br><br>The clinic has a calm, relaxing vibe and is very clean.<br><br>I have had a wonderful experience with the clinic and would highly recommend the team to anyone on their fertility journey!’

T Yang

3 November 2026, LWC Brentwood

‘We have used London Women's Clinic twice in the last two years for successful egg retrieval and two subsequent frozen embryo transfers. We have always been met with care, compassion and a personal approach. Every step from the initial consultation right through to the 7 week scan has been professional and polite, always accommodating our needs and timings. We can't thank the team enough for giving us such support towards creating our family.’

Lucy Richards

2 November 2026, LWC Tunbridge Wells

‘Myself and my husband owe it all to london womens clinic, they were amazing from start to finish. We previously were under another clinic and decided to make the change due to many reasons and we are so glad we did. They treat everyone as individuals, not everyones fertility journeys are the same. The small team at Colchester make it so personable not to mention how amazing all 4 women are that work here, their knowledge empathy and listening skills simply cannot be found at any other clinic. The list goes on as to why I would recommend LWC but everyone likes a to the point review. They genuinely care they dont treat you like a number and they help you through every hurdle that occurs. Our little boy wouldn't be possible without these 4, each of them play a bigger part than they realise. 💙’

Ellen Turrell

2 November 2026, LWC Colchester

‘Wonderful punch of people, caring, competent, and efficient in all they do. It feels we are all in a mission together and they are invested in the success of our pregnancy. Thank k you 🙏’

Yasmine Mora

30 October 2026, LWC London Bridge

‘I couldn’t speak more highly of the London Women’s Clinic Oxford! From the moment you walk in you are greeted with such a warm welcome. The reception area is bright and welcoming and the receptionist is lovely. All of the staff are so friendly, helpful and polite.<br><br>Going through this journey can be emotional, so having such a wonderful supportive, caring clinic to visit makes all the difference. Everyone goes above and beyond to make you feel comfortable and looked after.<br><br>I feel so lucky to have such a lovely team supporting me along the way. Thank you all! 🍀💗’

Louise

30 October 2026, LWC Oxford

‘Incredible service and professionals. They made me feel comfortable and safe the entire journey. Thank you!’

Luciana Lombardi

30 October 2026, LWC Cambridge

‘I had an absolutely amazing experience at LWC from start to finish! There are literally no wait times so we were able to get started pretty much straight away after consultation. The process was seamless, with a lot of flexibility if you need to change appt time. Nurses are amazing and so supportive. Special shout out to Kate and Chris who were so kind and made the whole experience so much better. Also the nurses on the ward were absolutely amazing but I can’t remember their names. I’m now discharged as I’m pregnant from my first try! However I will look forward to returning in the future for my second embryo which is currently frozen 😊’

Kathryn Jessica

27 October 2026, LWC Bromley

‘We we under the care of Canterbury LWC for all scans and blood tests and Bromley for egg collection and transfers. The team and Canterbury were particularly amazing, so supportive and reassuring throughout. No question was ever too much, they treated you as individuals and were caring and compassionate throughout the process. The receptionist were lovely, knew you from the offset by name, remembered you which makes a difficult process so much easier when you are treated as an individual.<br>We were NHS funded and I never felt we were treated any different to private patients.<br>The nursing staff at Bromley were also brilliant, I always felt so looked after through some really tough and emotional procedures. We were under the care of Dr Uppal who was excellent, explained everything clearly, gave us options and listened to our concerns.<br>Would highly recommend. Currently 26 weeks pregnant ☺️’

Rose S

25 October 2026, LWC Canterbury

‘We are incredibly grateful to London Women’s Clinic, Harrow, for helping make our dream of becoming parents come true. We are now blessed with a beautiful baby!<br><br>A special thank you to Dr Gill for the care, guidance and support throughout our IVF journey, and to Carla and Maria for making the entire process smooth and reassuring.<br><br>We had a wonderful experience and will always be thankful to the whole team. Highly recommend! ❤️’

P S

23 October 2026, LWC Harrow

‘LWC are fantastically supportive at every stage of your journey. They try to be as flexible as possible with appointments, giving good advice about supporting yourself (and partners) as you prepare for different procedures. It is a tough journey but Louise, Rute, Dr Arthi, Trianni, Dr Bishista and Ashley are incredibly supportive. Highly recommend them to anyone considering or needing fertility support.’

S W

23 October 2026, LWC Cambridge

‘I honestly cannot fault Kind IVF. From start to finish, I have been so incredibly impressed with the care, compassion and professionalism shown by the entire team. Going through IVF can be such an emotional and overwhelming journey, but they have made the whole experience feel so much more reassuring and positive.<br><br>Every step of the way, I have felt cared for, listened to and supported. The team have been amazing at answering questions, putting my mind at ease and making sure I felt comfortable throughout the process. You can really tell how much they care about their patients, and that makes such a huge difference during a journey that can be so personal and emotional.<br><br>I am so grateful to everyone at Kind IVF for everything they have done for us. Choosing them has been one of the best decisions we have made, and I genuinely couldn’t recommend them enough to anyone considering IVF. The standard of care has been outstanding, and I cannot thank them enough for helping us on this journey. ❤️<br><br>Thank you, Kind IVF, for being so amazing!’

Georgia Burt

22 October 2026, LWC Tunbridge Wells

‘I highly recommend the London Women's Clinic Brentwood. The staff were very supportive, patient, and always available to answer questions. They guided me through an emotional process with clear explanations and genuine care. The staff were always available and happy to help.’

S Begum

21 October 2026, LWC Brentwood

‘Choosing an IVF clinic is such a big decision and I'm so incredibly glad that we chose this one. IVF can be such an emotional and overwhelming journey but having a clinic that offers so much support and genuinely cares for you makes such a difference. The care and kindness that we have received has been exceptional.<br>We can't thank LWC Brentwood enough ❤️’

Laura Keary

21 October 2026, LWC Brentwood

‘I honestly can’t thank London Women’s Clinic enough for helping me achieve my lifelong dream of becoming a mum.<br>It wasn’t an easy journey, but the team were absolutely fantastic and supported me every step of the way. Their kindness, care and reassurance made such a difference during what was a really emotional and challenging time. I always felt supported and in safe hands.<br>A special thank you to Carla, Ana-Maria and Dr Goswami. You have all been absolutely fantastic and I am so grateful for everything you have done for me. I’ll never forget the support and care you have shown me during such an important and emotional journey.<br>Thank you all from the bottom of my heart for helping me achieve something I have wanted for as long as I can remember. It means more to me than words can say. I would recommend London Women’s Clinic to anyone going through their own fertility journey.’

Sarah

21 October 2026, LWC Harrow

‘We started our treatment in July, and I have had a very positive experience with this clinic. Lorraine on reception especially made me feel like nothing was too much trouble and always knew me by name which is such a nice personal touch, especially at such a sensitive time. Along with Dr Safwat Ashour he always recommended the best treatment for us and just had such a kind caring attitude towards us while explaining our options and being very honest with us too. One of the nurses (so sorry I can’t remember your name) she only recently started in July and I felt so at home with her and cared for. To finish off we are currently pregnant with our IVF miracle all thanks you this clinic. Thank you all so much, no thanks would ever be enough for the gift you have given us!’

Sophie Jay

21 October 2026, LWC Darlington

‘Very professional and very welcoming, and very clean I was given time to feel relaxed and I didn't feel like I had to rush this made me feel very comfortable.’

Ryan Harmer

21 October 2026, LWC Brighton

4.5

FAQs about the Implantation Clinic

In some cases, no issues are identified. Rarely, tests may need to be repeated to provide further insight.

Laboratory analysis typically takes 4–5 weeks, followed by a consultation to discuss your personalised treatment plan.

Most patients experience only mild discomfort, similar to a smear test. Our team supports you throughout to ensure you feel comfortable and informed.

If you’ve had one or more failed embryo transfers despite good quality embryos, our doctors can review your history and discuss whether personalised endometrial testing could provide insight.

Let us help you try again

Book your consultation at the Implantation Clinic to explore why previous embryo transfers may not have succeeded. We will review your history, conduct any necessary assessments and create a personalised treatment plan tailored to your reproductive journey.